The Faculty of Biology UGM held the 8th biotalk, on Wednesday, 7 October 2020. The invited speakers were Dr. Barano Siswa Sulistyawan, M.Sc. (Conservation Manager, WWF Indonesia; Alumni F. Biology UGM 1990), Prof. Drs. Rosichon Ubaidillah, M.Phill., Ph.D. (Senior Researcher, Center for Biological Research, LIPI; Alumni F. Biology UGM 1983), and Matin Nuhamunada, M.Sc. (Lecturer at the Faculty of Biology UGM; Alumni F. Biology UGM 2010). The first speaker, Prof. Drs. Rosichon Ubaidillah, M.Phill., Ph.D. explained that big data development opens up new opportunities for biological research. Big Data will give birth to a new paradigm in biological research. Barano Siswa Sulistyawan, M.Sc. as the second speaker, discussed the potency of Big Data application in Indonesia. The last speaker, Matin Nuhamunada, M.Sc., presented about the benefit of using Big Data in biotechnology research.